Separated from God

"... God is on one side and all the people are on the other side ..." 1 Timothy 2:5

The Bible says:

“This is good, and pleases God our Savior, who wants all men to be saved and to come to a knowledge of the truth.” 2 Timothy 2:3,4

Yes, God loves us and wants all of us to be saved. But man is separated from God and His love.

Why are we separated? How do we get to God and His love?